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Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.
Garai, János; Radnai, Balázs; Vámos, Eszter; Kovács, Dominika; Vántus, Viola Bagóné; Rumbus, Zoltán; Pákai, Eszter; Garami, András; Gulyás-Fekete, Gergely; Agócs, Attila; Krekó, Marcell; Zaman, Khadiza; Prókai, László; Orfi, László; Jakus, Péter B; Lóránd, Tamás.
Afiliação
  • Garai J; Department of Pathophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: janos.garai@gmail.com.
  • Radnai B; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: balazs.radnai@aok.pte.hu.
  • Vámos E; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: eszter.vamos@aok.pte.hu.
  • Kovács D; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: dominika.kovacs@aok.pte.hu.
  • Vántus VB; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: viola.vantus@aok.pte.hu.
  • Rumbus Z; Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: zoltan.rumbus@aok.pte.hu.
  • Pákai E; Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: eszter.pakai@aok.pte.hu.
  • Garami A; Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: andras.garami@aok.pte.hu.
  • Gulyás-Fekete G; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: gergely.gulyas@aok.pte.hu.
  • Agócs A; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: attila.agocs@aok.pte.hu.
  • Krekó M; Department of Pharmaceutical Chemistry, Semmelweis University, 9 Hogyes E. str., Budapest, H-1092, Hungary. Electronic address: kreko.marcell@pharma.semmelweis-univ.hu.
  • Zaman K; Department of Pharmacology and Neuroscience, The University of North Texas Health Science Centre, Fort Worth, TX, USA. Electronic address: khadiza.zaman@unthsc.edu.
  • Prókai L; Department of Pharmacology and Neuroscience, The University of North Texas Health Science Centre, Fort Worth, TX, USA. Electronic address: laszlo.prokai@unthsc.edu.
  • Orfi L; Department of Pharmaceutical Chemistry, Semmelweis University, 9 Hogyes E. str., Budapest, H-1092, Hungary. Electronic address: orfi.laszlo@pharma.semmelweis-univ.hu.
  • Jakus PB; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: peter.jakus@aok.pte.hu.
  • Lóránd T; Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: lorand.tamas@gmail.com.
Eur J Med Chem ; 247: 115050, 2023 Feb 05.
Article em En | MEDLINE | ID: mdl-36587420
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Séptico / Fatores Inibidores da Migração de Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de publicação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Séptico / Fatores Inibidores da Migração de Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de publicação: França