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The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow.
Pravdivtseva, Mariya S; Pravdivtsev, Andrey N; Peters, Sönke; Hensler, Johannes; Larsen, Naomi; Hövener, Jan-Bernd; Jansen, Olav; Wodarg, Fritz.
Afiliação
  • Pravdivtseva MS; Department of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), 54186University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.
  • Pravdivtsev AN; Department of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), 54186University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.
  • Peters S; Department of Radiology and Neuroradiology, 9179University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
  • Hensler J; Department of Radiology and Neuroradiology, 9179University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
  • Larsen N; Department of Radiology and Neuroradiology, 9179University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
  • Hövener JB; Department of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), 54186University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.
  • Jansen O; Department of Radiology and Neuroradiology, 9179University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
  • Wodarg F; Department of Radiology and Neuroradiology, 9179University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
Interv Neuroradiol ; : 15910199221145985, 2023 Jan 03.
Article em En | MEDLINE | ID: mdl-36594503
ABSTRACT

BACKGROUND:

Recently, a novel intrasaccular device (contour neurovascular system, contour) was introduced to treat intracranial aneurysms. Contour is placed at thе aneurysm neck and reduces the intraaneurysmal blood inflow. Contour comes in a range of sizes to target different aneurysms. The efficiency of altering flow with contour and the effect of device size have not yet been investigated. Therefore, we studied the effect of the device size with patient-based aneurysm models using 2D digital subtraction angiography (DSA).

METHODS:

Three patient-based aneurysm models with necks ranging from 2.7 to 9.7 mm were produced, providing standardized testing conditions. Contours with diameters of 5, 11, and 14 mm were implanted into the models, four of each size. 2D DSA images were acquired before and after implanting contour (15 frames/s, manual contrast injection). After injecting angiographic contrast agent, the DSA signal was recorded over time to calculate the contrast washout time (WOT), which is a measure of flow diversion efficiency.

RESULTS:

All contour devices caused contrast agent stasis and increased WOT in aneurysm sac (p-value = 0.0005). The median relative WOT was largest for 5-mm contour (6.6 ± 3.2) and similar for 11-mm contour (3.4 ± 2.6) and 14-mm contour (3.2 ± 3.8). The implantation procedure might affect WOT values even for contours of the same size; the overall relative WOT ranged between 1.5 and 10.89.

CONCLUSION:

The 5-mm contour showed the longest WOT value in our study, while no apparent difference between 11-mm contour and 14-mm contour was found.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Interv Neuroradiol Assunto da revista: NEUROLOGIA / RADIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Interv Neuroradiol Assunto da revista: NEUROLOGIA / RADIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha