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The genetic history of Scandinavia from the Roman Iron Age to the present.
Rodríguez-Varela, Ricardo; Moore, Kristjan H S; Ebenesersdóttir, S Sunna; Kilinc, Gulsah Merve; Kjellström, Anna; Papmehl-Dufay, Ludvig; Alfsdotter, Clara; Berglund, Birgitta; Alrawi, Loey; Kashuba, Natalija; Sobrado, Verónica; Lagerholm, Vendela Kempe; Gilbert, Edmund; Cavalleri, Gianpiero L; Hovig, Eivind; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Hansen, Thomas F; Werge, Thomas; Munters, Arielle R; Bernhardsson, Carolina; Skar, Birgitte; Christophersen, Axel; Turner-Walker, Gordon; Gopalakrishnan, Shyam; Daskalaki, Eva; Omrak, Ayça; Pérez-Ramallo, Patxi; Skoglund, Pontus; Girdland-Flink, Linus; Gunnarsson, Fredrik; Hedenstierna-Jonson, Charlotte; Gilbert, M Thomas P; Lidén, Kerstin; Jakobsson, Mattias; Einarsson, Lars; Victor, Helena; Krzewinska, Maja; Zachrisson, Torun; Storå, Jan; Stefánsson, Kári; Helgason, Agnar; Götherström, Anders.
Afiliação
  • Rodríguez-Varela R; Centre for Palaeogenetics, 106 91 Stockholm, Sweden; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden. Electronic address: ricardo.rodriguez.varela@arklab.su.se.
  • Moore KHS; deCODE Genetics/AMGEN, Inc., 102 Reykjavik, Iceland.
  • Ebenesersdóttir SS; deCODE Genetics/AMGEN, Inc., 102 Reykjavik, Iceland; Department of Anthropology, University of Iceland, 102 Reykjavik, Iceland.
  • Kilinc GM; Department of Bioinformatics, Graduate School of Health Sciences, Hacettepe University, 06100 Ankara, Turkey.
  • Kjellström A; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Papmehl-Dufay L; Linnaeus University, 351 95 Kalmar, Sweden.
  • Alfsdotter C; Department of Archaeology, Bohusläns Museum, Museigatan 1, 451 19 Udevalla, Sweden.
  • Berglund B; Department of Archaeology and Cultural History, NTNU University Museum, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
  • Alrawi L; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Kashuba N; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden; Department of Archaeology and Ancient History, Archaeology, Uppsala University, 752 38 Uppsala, Sweden; Department of Organismal Biology, Human Evolution, and SciLife Lab, Uppsala University, 75236 Uppsal
  • Sobrado V; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Lagerholm VK; Centre for Palaeogenetics, 106 91 Stockholm, Sweden; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Gilbert E; School of Pharmacy and Biomolecular Sciences, RCSI, D02 YN77 Dublin, Ireland; FutureNeuro SFI Research Centre, RCSI, D02 YN77 Dublin, Ireland.
  • Cavalleri GL; School of Pharmacy and Biomolecular Sciences, RCSI, D02 YN77 Dublin, Ireland; FutureNeuro SFI Research Centre, RCSI, D02 YN77 Dublin, Ireland.
  • Hovig E; Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, 0424 Oslo, Norway; Centre for Bioinformatics, Department of Informatics, University of Oslo, 166 0450 Oslo, Norway.
  • Kockum I; Center for Molecular Medicine, Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Olsson T; Center for Molecular Medicine, Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Alfredsson L; Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
  • Hansen TF; Institute of Biological Psychiatry, Copenhagen Mental Health Services, 4000 Roskilde, Denmark; Danish Headache Center, Department of Neurology, Copenhagen University Hospital, 2600 Glostrup, Denmark.
  • Werge T; Institute of Biological Psychiatry, Copenhagen Mental Health Services, 4000 Roskilde, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen 2200, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, 8210 Aarhus, Denmark.
  • Munters AR; Department of Organismal Biology, Human Evolution, and SciLife Lab, Uppsala University, 75236 Uppsala, Sweden.
  • Bernhardsson C; Department of Organismal Biology, Human Evolution, and SciLife Lab, Uppsala University, 75236 Uppsala, Sweden.
  • Skar B; Department of Archaeology and Cultural History, NTNU University Museum, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
  • Christophersen A; Department of Archaeology and Cultural History, NTNU University Museum, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
  • Turner-Walker G; Department of Archaeology and Anthropology National Museum of Natural Science, 404023 Taichung City, Taiwan.
  • Gopalakrishnan S; Center for Evolutionary Hologenomics, the GLOBE Institute, University of Copenhagen, 1353 Copenhagen, Denmark.
  • Daskalaki E; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Omrak A; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Pérez-Ramallo P; isoTROPIC Research Group, Department of Archaeology, Max Planck Institute for Geoanthropology, 07745 Jena, Germany; Department of Medical and Surgical Specialities, Faculty of Medicine and Nursing, University of the Basque Country (EHU), Donostia-San Sebastián 20014, Spain.
  • Skoglund P; Francis Crick Institute, London NW1 1AT, UK.
  • Girdland-Flink L; Department of Archaeology, School of Geosciences, University of Aberdeen, AB24 3FX Aberdeen, UK; School of Biological and Environmental Sciences, Liverpool John Moores University, L3 3AF Liverpool, UK.
  • Gunnarsson F; Department of Museum Archaeology, Kalmar County Museum, Box 104, Kalmar 39121, Sweden.
  • Hedenstierna-Jonson C; Department of Archaeology and Ancient History, Archaeology, Uppsala University, 752 38 Uppsala, Sweden.
  • Gilbert MTP; Center for Evolutionary Hologenomics, the GLOBE Institute, University of Copenhagen, 1353 Copenhagen, Denmark; Department of Natural History, NTNU University Museum, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
  • Lidén K; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Jakobsson M; Department of Organismal Biology, Human Evolution, and SciLife Lab, Uppsala University, 75236 Uppsala, Sweden.
  • Einarsson L; Kronan, Marine Archaeological Department, Kalmar County Museum, Box 104, Kalmar S-39121, Sweden.
  • Victor H; Department of Museum Archaeology, Kalmar County Museum, Box 104, Kalmar 39121, Sweden.
  • Krzewinska M; Centre for Palaeogenetics, 106 91 Stockholm, Sweden; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Zachrisson T; Upplandsmuseet/County Museum of Uppland, Uppsala 753 10, Sweden.
  • Storå J; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden.
  • Stefánsson K; deCODE Genetics/AMGEN, Inc., 102 Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.
  • Helgason A; deCODE Genetics/AMGEN, Inc., 102 Reykjavik, Iceland; Department of Anthropology, University of Iceland, 102 Reykjavik, Iceland. Electronic address: agnar.helgason@decode.is.
  • Götherström A; Centre for Palaeogenetics, 106 91 Stockholm, Sweden; Department of Archaeology and Classical Studies, Stockholm University, 10691 Stockholm, Sweden. Electronic address: anders.gotherstrom@arklab.su.se.
Cell ; 186(1): 32-46.e19, 2023 01 05.
Article em En | MEDLINE | ID: mdl-36608656
We investigate a 2,000-year genetic transect through Scandinavia spanning the Iron Age to the present, based on 48 new and 249 published ancient genomes and genotypes from 16,638 modern individuals. We find regional variation in the timing and magnitude of gene flow from three sources: the eastern Baltic, the British-Irish Isles, and southern Europe. British-Irish ancestry was widespread in Scandinavia from the Viking period, whereas eastern Baltic ancestry is more localized to Gotland and central Sweden. In some regions, a drop in current levels of external ancestry suggests that ancient immigrants contributed proportionately less to the modern Scandinavian gene pool than indicated by the ancestry of genomes from the Viking and Medieval periods. Finally, we show that a north-south genetic cline that characterizes modern Scandinavians is mainly due to the differential levels of Uralic ancestry and that this cline existed in the Viking Age and possibly earlier.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Humano Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Humano Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos