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Induction and Maintenance Treatment With Upadacitinib Improves Health-Related Quality of Life in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 Study Results.
Panés, Julian; Loftus, Edward V; Higgins, Peter D R; Lindsay, James O; Zhou, Wen; Yao, Xuan; Ilo, Dapo; Phillips, Charles; Tran, Jacinda; Sanchez Gonzalez, Yuri; Vermeire, Séverine.
Afiliação
  • Panés J; Inflammatory Bowel Disease Unit, Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Loftus EV; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
  • Higgins PDR; Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Lindsay JO; Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.
  • Zhou W; AbbVie Inc, North Chicago, IL, USA.
  • Yao X; AbbVie Inc, North Chicago, IL, USA.
  • Ilo D; AbbVie Inc, North Chicago, IL, USA.
  • Phillips C; AbbVie Inc, North Chicago, IL, USA.
  • Tran J; AbbVie and the Comparative Health Outcomes, Policy, and Economics Institute, University of Washington, Seattle, WA, USA.
  • Sanchez Gonzalez Y; AbbVie Inc, North Chicago, IL, USA.
  • Vermeire S; Department of Gastroenterology and Hepatology, University Hospital Leuven, Leuven, Belgium.
Inflamm Bowel Dis ; 29(9): 1421-1430, 2023 09 01.
Article em En | MEDLINE | ID: mdl-36645051
Patients with moderate-to-severe ulcerative colitis who received upadacitinib induction treatment demonstrated clinically meaningful improvements across multiple health-related quality of life assessments, as early as induction week 2, that persisted with maintenance treatment to 52 weeks, compared with placebo.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha País de publicação: Reino Unido