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Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
Luukkonen, Panu K; Sakuma, Ikki; Gaspar, Rafael C; Mooring, Meghan; Nasiri, Ali; Kahn, Mario; Zhang, Xian-Man; Zhang, Dongyan; Sammalkorpi, Henna; Penttilä, Anne K; Orho-Melander, Marju; Arola, Johanna; Juuti, Anne; Zhang, Xuchen; Yimlamai, Dean; Yki-Järvinen, Hannele; Petersen, Kitt Falk; Shulman, Gerald I.
Afiliação
  • Luukkonen PK; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Sakuma I; Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki 00290, Finland.
  • Gaspar RC; Minerva Foundation Institute for Medical Research, Helsinki 00290, Finland.
  • Mooring M; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Nasiri A; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Kahn M; Department of Pediatrics, The Yale Liver Center, Yale School of Medicine, New Haven 06520, CT.
  • Zhang XM; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Zhang D; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Sammalkorpi H; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Penttilä AK; Department of Internal Medicine, Yale School of Medicine, New Haven 06520, CT.
  • Orho-Melander M; Department of Abdominal Surgery, Helsinki University Hospital and University of Helsinki, Helsinki 00290, Finland.
  • Arola J; Department of Abdominal Surgery, Helsinki University Hospital and University of Helsinki, Helsinki 00290, Finland.
  • Juuti A; Department of Clinical Sciences, Diabetes and Endocrinology, University Hospital Malmö, Lund University, Malmö 21428, Sweden.
  • Zhang X; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki 00290, Finland.
  • Yimlamai D; Department of Abdominal Surgery, Helsinki University Hospital and University of Helsinki, Helsinki 00290, Finland.
  • Yki-Järvinen H; Department of Pathology, Yale School of Medicine, New Haven 06520, CT.
  • Petersen KF; Department of Pediatrics, The Yale Liver Center, Yale School of Medicine, New Haven 06520, CT.
  • Shulman GI; Minerva Foundation Institute for Medical Research, Helsinki 00290, Finland.
Proc Natl Acad Sci U S A ; 120(4): e2217543120, 2023 Jan 24.
Article em En | MEDLINE | ID: mdl-36669104
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos