Tailoring Apixaban in Nanostructured Lipid Carrier Enhancing Its Oral Bioavailability and Anticoagulant Activity.

Zaky, Mohamed F; Megahed, Mohamed A; Hammady, Taha M; Gad, Shadeed; Ghorab, Mamdouh Mostafa; El-Say, Khalid M

Zaky, Mohamed F; Megahed, Mohamed A; Hammady, Taha M; Gad, Shadeed; Ghorab, Mamdouh Mostafa; El-Say, Khalid M.

Afiliação

Zaky MF; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Megahed MA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Hammady TM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Gad S; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Ghorab MM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
El-Say KM; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Pharmaceutics ; 15(1)2022 Dec 27.

Article em En | MEDLINE | ID: mdl-36678709

Palavras-chave

anticoagulant activity; apixaban; boxbehnken design; in vivo pharmacokinetic; industrial development; nanostructured lipid carrier; venous thromboembolism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito País de publicação: Suíça

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