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Analytical dosimetric study of intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) for prostate cancer.
Samir, Fady; Meaz, Talaat M; Hussiny, Fathi AEl; Ahmed, Ahmed A; Mahmoud, Amr A; Refaat, Tamer; Gawish, Ahmed; Abouegylah, Mohamed.
Afiliação
  • Samir F; Alexandria Clinical Oncology Department, Alexandria University, Alexandria, Egypt.
  • Meaz TM; Physics Department Faculty of Science, Tanta University, Tanta, Egypt.
  • Hussiny FA; Physics Department Faculty of Science, Tanta University, Tanta, Egypt.
  • Ahmed AA; Ayadi Almostakbal Oncology Center, Alexandria, Egypt.
  • Mahmoud AA; Department of Clinical Oncology, Kafr Elsheikh University, Kafr El-Sheikh, Egypt.
  • Refaat T; Department of Radiation Oncology, Loyola University Chicago, Chicago, USA.
  • Gawish A; Department of Radiation Oncology, University Hospital Magdeburg, Magdeburg, Germany. ahmed.gawish@med.ovgu.de.
  • Abouegylah M; Alexandria Clinical Oncology Department, Alexandria University, Alexandria, Egypt.
J Cancer Res Clin Oncol ; 149(9): 6239-6246, 2023 Aug.
Article em En | MEDLINE | ID: mdl-36702973
PURPOSE: The study aimed to compare the dosimetric results and treatment delivery efficiency among four techniques to explore the preferred technique in prostate treatment. MATERIALS AND METHODS: 7 IMRT, 9 IMRT, 1 ARC, and 2 ARC plans were created for 30 prostate cancer patients using the Eclipse™ treatment planning system (Varian Medical Systems). All the plans were designed to deliver 80.0 Gy in 40 fractions to the prostate planning target volume (PTV). Target coverage, organs at risk (OARs), number of monitor units, homogeneity, and conformity were compared across the four techniques to assess the quality of the plans. RESULTS: The study revealed better Planning Target Volume (PTV) dose coverage in the VMAT-2A than in the other plans. At the same time, VMAT-2A plans were found to be significantly lower in terms of Bladder and rectum doses than other techniques. In addition, VMAT has the advantage of considerably reducing the number of monitor units and treatment time. CONCLUSION: For prostate cancer, VMAT may offer a favorable dose gradient profile, conformity, and MU and treatment time compared to IMRT.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Radioterapia de Intensidade Modulada Limite: Humans / Male Idioma: En Revista: J Cancer Res Clin Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Egito País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Radioterapia de Intensidade Modulada Limite: Humans / Male Idioma: En Revista: J Cancer Res Clin Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Egito País de publicação: Alemanha