[Action of haloperidol on the ultrastructure of areas of the dopaminergic system of the brain]. / Deistvie galoperidola na ul'trastrukturu nekotorykh oblastei dofaminergicheskoi sistemy mozga.
Zh Nevropatol Psikhiatr Im S S Korsakova
; 87(7): 1028-31, 1987.
Article
em Ru
| MEDLINE
| ID: mdl-3673382
ABSTRACT
The ultrastructure of the olfactory tubercle was investigated in patients receiving prolonged (3-weeks-long) treatment with low doses (0.1 mg/kg) of haloperidol. This therapy was mostly associated with changes in the neuronal processes and glial cells. It has been found that ultrastructural rearrangement in neurons of the olfactory tubercle is functional in nature which indicates the change in the efficacy of synaptic transmission and in metabolic processes. It is postulated that chronic administration of low doses of haloperidol induces adaptive alterations mediated by DA receptor block.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Dopamina
/
Receptores Dopaminérgicos
/
Haloperidol
Limite:
Animals
Idioma:
Ru
Revista:
Zh Nevropatol Psikhiatr Im S S Korsakova
Assunto da revista:
NEUROLOGIA
/
PSIQUIATRIA
Ano de publicação:
1987
Tipo de documento:
Article