NRXN1 depletion in the medial prefrontal cortex induces anxiety-like behaviors and abnormal social phenotypes along with impaired neurite outgrowth in rat.

Wu, Di; Zhu, Jiansheng; You, Lianghui; Wang, Jingyu; Zhang, Sufen; Liu, Zhonghui; Xu, Qu; Yuan, Xiaojie; Yang, Lei; Wang, Wei; Tong, Meiling; Hong, Qin; Chi, Xia

Wu, Di; Zhu, Jiansheng; You, Lianghui; Wang, Jingyu; Zhang, Sufen; Liu, Zhonghui; Xu, Qu; Yuan, Xiaojie; Yang, Lei; Wang, Wei; Tong, Meiling; Hong, Qin; Chi, Xia.

Afiliação

Wu D; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Zhu J; The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, China.
You L; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Wang J; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Zhang S; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Liu Z; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Xu Q; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Yuan X; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Yang L; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Wang W; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Tong M; The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hong Q; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Chi X; Department of Child Healthcare, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China. rambler_hq@163.com.

J Neurodev Disord ; 15(1): 6, 2023 02 03.

Article em En | MEDLINE | ID: mdl-36737720

Assuntos

Transtorno do Espectro Autista; Animais; Ratos; Ansiedade; Transtorno do Espectro Autista/genética; Proteínas de Ligação ao Cálcio/genética; Moléculas de Adesão de Célula Nervosa/genética; Crescimento Neuronal; Fenótipo; Córtex Pré-Frontal; Proteômica

Palavras-chave

Anxiety-like behavior; Cell adhesion molecules; NRXN1; Neurite outgrowth; Neurodevelopmental disorders; Social behavior

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno do Espectro Autista Limite: Animals Idioma: En Revista: J Neurodev Disord Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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