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Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies.
Painter, Mark M; Johnston, Timothy S; Lundgreen, Kendall A; Santos, Jefferson J S; Qin, Juliana S; Goel, Rishi R; Apostolidis, Sokratis A; Mathew, Divij; Fulmer, Bria; Williams, Justine C; McKeague, Michelle L; Pattekar, Ajinkya; Goode, Ahmad; Nasta, Sean; Baxter, Amy E; Giles, Josephine R; Skelly, Ashwin N; Felley, Laura E; McLaughlin, Maura; Weaver, Joellen; Kuthuru, Oliva; Dougherty, Jeanette; Adamski, Sharon; Long, Sherea; Kee, Macy; Clendenin, Cynthia; da Silva Antunes, Ricardo; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Huang, Alexander C; Rader, Daniel J; Hensley, Scott E; Bates, Paul; Greenplate, Allison R; Wherry, E John.
Afiliação
  • Painter MM; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Johnston TS; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Lundgreen KA; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Santos JJS; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Qin JS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA; Immunology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Goel RR; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Apostolidis SA; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Mathew D; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Fulmer B; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Williams JC; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • McKeague ML; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Pattekar A; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Goode A; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Nasta S; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Baxter AE; Division of Rheumatology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Giles JR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Skelly AN; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Felley LE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • McLaughlin M; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Weaver J; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Kuthuru O; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Dougherty J; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Adamski S; Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Long S; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Kee M; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Clendenin C; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • da Silva Antunes R; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Grifoni A; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Weiskopf D; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Sette A; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Huang AC; Division of Infectious Disease, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Rader DJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Hensley SE; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
  • Bates P; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Wherry EJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA, USA.
bioRxiv ; 2023 Feb 06.
Article em En | MEDLINE | ID: mdl-36798171

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos