Association between basketball playing position and ACTN3 R577X polymorphism in athletes of first division Brazilian Basketball League.
Gene
; 863: 147302, 2023 May 05.
Article
em En
| MEDLINE
| ID: mdl-36813062
ABSTRACT
INTRODUCTION:
Genetic-association studies have shown that some polymorphisms are associated with different aspects of athletic performance, including very specific features, such as players' position in team sports, like soccer, rugby, and Australian football. However, this type of association has not been investigated in Basketball yet. The present study analyzed the association of ACTN3 R577X, AGT M268T, ACE I/D and BDKRB2+9/-9 polymorphisms with the position of basketball players.METHODS:
One hundred fifty-two male athletes from 11 teams of the first division of Brazilian Basketball League and 154 male Brazilian controls were genotyped. The analyses of the ACTN3 R577X and AGT M268T were performed by the allelic discrimination method, while ACE I/D and BDKRB2+9/-9 by conventional PCR followed by electrophorese in agarose gel.RESULTS:
The results showed a significant effect of height on all positions and an association between the genetic polymorphisms analyzed and basketball positions. In addition, a significantly higher frequency of ACTN3 577XX genotype was observed in Point Guards. Also, compared to Point Guard, ACTN3 RR and RX were more prevalent in the Shooting Guard and Small Forward group and RR genotype was also more prevalent in the Power Forward and Center group.CONCLUSION:
The main finding of our study was the positive association of ACTN3 R577X polymorphism and basketball playing position, and a suggestion of genotypes related to strength/power performance with post players and genotypes related to endurance performance with point guard players.Palavras-chave
Texto completo:
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Basquetebol
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
/
Male
País/Região como assunto:
America do sul
/
Brasil
/
Oceania
Idioma:
En
Revista:
Gene
Ano de publicação:
2023
Tipo de documento:
Article