Cancer-associated fibroblasts facilitate DNA damage repair by promoting the glycolysis in non-small cell lung cancer.

Zhang, Hongfang; Zhang, Ke; Qiu, Liqing; Yue, Jing; Jiang, Hong; Deng, Qinghua; Zhou, Rongjing; Yin, Zihao; Ma, Shenglin; Ke, Yuehai

Zhang, Hongfang; Zhang, Ke; Qiu, Liqing; Yue, Jing; Jiang, Hong; Deng, Qinghua; Zhou, Rongjing; Yin, Zihao; Ma, Shenglin; Ke, Yuehai.

Afiliação

Zhang H; Hangzhou Cancer Institution, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China; Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Me
Zhang K; Department of Radiation Oncology, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.
Qiu L; Hangzhou Cancer Institution, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.
Yue J; Hangzhou Cancer Institution, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.
Jiang H; Department of Cardiothoracic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Deng Q; Department of Radiation Oncology, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.
Zhou R; Department of Pathology, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.
Yin Z; Zhejiang Chinese Medical University, Hangzhou 310053, China.
Ma S; Hangzhou Cancer Institution, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China; Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Me
Ke Y; Department of Pathology and Pathophysiology and Department of Respiratory Medicine at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address: yke@zju.edu.cn.

Biochim Biophys Acta Mol Basis Dis ; 1869(5): 166670, 2023 06.

Article em En | MEDLINE | ID: mdl-36822449

Assuntos

Fibroblastos Associados a Câncer; Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/radioterapia; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Fibroblastos Associados a Câncer/patologia; beta Catenina/genética; beta Catenina/metabolismo; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/radioterapia; Neoplasias Pulmonares/metabolismo; Reparo do DNA; Via de Sinalização Wnt/genética; Dano ao DNA; Glicólise; Microambiente Tumoral

Palavras-chave

CAFs; DNA damage response; Glycolysis; Midkine; NSCLC

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Fibroblastos Associados a Câncer / Neoplasias Pulmonares Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2023 Tipo de documento: Article País de publicação: Holanda

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