Screening methods for congenital anomalies in low and lower-middle income countries: A systematic review.
J Pediatr Surg
; 58(5): 986-993, 2023 May.
Article
em En
| MEDLINE
| ID: mdl-36822972
ABSTRACT
INTRODUCTION:
Surgically correctable congenital anomalies are responsible for a significant burden of morbidity and mortality in children from low-and lower-middle-income countries (LMICs). Early identification through fetal and neonatal screening is critical to reducing death and disability. This study aims to identify feasible screening methods for surgically correctable congenital anomalies in LMICs.METHODS:
A systematic search looking at screening for congenital anomalies in LMIC was conducted in seven databases from 2000 until May 25, 2020, with no language restriction. All articles discussing screening methods for surgically correctable congenital anomalies in LMICs were included. Articles were screened by two independent contributors using Rayyan software, with a third contributor resolving conflicts. Feasibility of the screening method and its risk of bias were assessed using the MINORS scale.RESULTS:
Of 3473 articles, 24 were included in the full-text review. Nine screening methods (three prenatal and six postnatal) were identified - the most frequently utilized being physician clinical examination (45.8%), pulse oximetry (33.3%) and fetal ultrasound (20.8%). The use of a birth defect picture toolkit was the most feasible screening method. The risk of bias scale yielded an average of 11.9 points, which corresponds to a moderate level of bias.CONCLUSION:
Despite clear benefits, prenatal and neonatal screening methods are infrequently used in LMICs to identify surgically correctable congenital anomalies in neonates, likely due to financial, material, and human resource constraints. Further research into the development of low-cost feasible methods is needed within these settings. PROSPERO REGISTRATION NUMBER CRD42020192051. TYPE OF STUDY Systematic review. LEVEL OF EVIDENCE IV.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triagem Neonatal
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Países em Desenvolvimento
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Risk_factors_studies
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Screening_studies
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Systematic_reviews
Aspecto:
Determinantes_sociais_saude
Limite:
Child
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Female
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Humans
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Newborn
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Pregnancy
Idioma:
En
Revista:
J Pediatr Surg
Ano de publicação:
2023
Tipo de documento:
Article