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MicroRNA-128 suppresses tau phosphorylation and reduces amyloid-beta accumulation by inhibiting the expression of GSK3ß, APPBP2, and mTOR in Alzheimer's disease.
Li, Siwen; Poon, Chi Him; Zhang, Zhigang; Yue, Ming; Chen, Ruijun; Zhang, Yalun; Hossain, Md Farhad; Pan, Yining; Zhao, Jun; Rong, Lei; Chu, Leung Wing; Shea, Yat Fung; Rogaeva, Ekaterina; Tu, Jie; St George-Hyslop, Peter; Lim, Lee Wei; Song, You-Qiang.
Afiliação
  • Li S; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Poon CH; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhang Z; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Yue M; The Brain Cognition and Brain Disease Institute (BCBDI), CAS Key Laboratory of Brain Connectome and Manipulation, Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research In
  • Chen R; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhang Y; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Hossain MF; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Pan Y; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhao J; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Rong L; Department of Clinical Immunology, Third Hospital of Sun Yat-sen University, Guangzhou, China.
  • Chu LW; Department of Medicine, The University of Hongkong-Shenzhen Hospital, Shenzhen, China.
  • Shea YF; Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
  • Rogaeva E; Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
  • Tu J; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • St George-Hyslop P; The Brain Cognition and Brain Disease Institute (BCBDI), CAS Key Laboratory of Brain Connectome and Manipulation, Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research In
  • Lim LW; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Song YQ; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
CNS Neurosci Ther ; 29(7): 1848-1864, 2023 07.
Article em En | MEDLINE | ID: mdl-36880288

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: CNS Neurosci Ther Assunto da revista: NEUROLOGIA / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: CNS Neurosci Ther Assunto da revista: NEUROLOGIA / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido