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Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR-/- mice.
Thompson, Dawn; Mahmood, Shehroz; Morrice, Nicola; Kamli-Salino, Sarah; Dekeryte, Ruta; Hoffmann, Philip A; Doherty, Mary K; Whitfield, Philip D; Delibegovic, Mirela; Mody, Nimesh.
Afiliação
  • Thompson D; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK. dthompson@abdn.ac.uk.
  • Mahmood S; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Morrice N; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Kamli-Salino S; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Dekeryte R; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Hoffmann PA; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Doherty MK; Lipidomics Research Facility, Department of Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, IV2 3JH, UK.
  • Whitfield PD; Lipidomics Research Facility, Department of Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, IV2 3JH, UK.
  • Delibegovic M; Glasgow Polyomics, University of Glasgow, Garscube Campus, Glasgow, G61 1QH, UK.
  • Mody N; Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
Sci Rep ; 13(1): 3937, 2023 03 09.
Article em En | MEDLINE | ID: mdl-36894641

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Fenretinida / Aterosclerose / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Fenretinida / Aterosclerose / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido