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Non-stoichiometric carbamazepine cocrystal hydrates of 3,4-/3,5-dihydroxybenzoic acids: coformer-water exchange.
Rajbongshi, Trishna; Sarmah, Kashyap Kumar; Das, Susobhan; Deka, Poonam; Saha, Arijit; Saha, Binoy K; Puschmann, Horst; Reddy, C Malla; Thakuria, Ranjit.
Afiliação
  • Rajbongshi T; Department of Chemistry, Gauhati University, Guwahati, 781014, India. ranjit.thakuria@gmail.com.
  • Sarmah KK; Department of Chemistry, Behali Degree College, Borgang, Biswanath, 784167, Assam, India.
  • Das S; Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, 741246, India. cmallareddy@gmail.com.
  • Deka P; Department of Chemistry, Gauhati University, Guwahati, 781014, India. ranjit.thakuria@gmail.com.
  • Saha A; Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, 741246, India. cmallareddy@gmail.com.
  • Saha BK; Department of Chemistry, Pondicherry University, Pondicherry, India.
  • Puschmann H; Department of Chemistry, Pondicherry University, Pondicherry, India.
  • Reddy CM; OlexSys Ltd, Durham University, South Road, Durham, DH1 3LE, UK.
  • Thakuria R; Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, 741246, India. cmallareddy@gmail.com.
Chem Commun (Camb) ; 59(26): 3902-3905, 2023 Mar 28.
Article em En | MEDLINE | ID: mdl-36919569
ABSTRACT
The cocrystallisation of carbamazepine (CBZ) with 3,4-/3,5-dihydroxybenzoic acids (34/35DHBA) with different stoichiometries formed molecular alloys, exchanging a water molecule, in their isostructural CBZ dihydrate form. Furthermore, we show a correlation between the mechanical properties of the CBZ-DHBA cocrystals with the amount of coformer present.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia