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Low-dose nano-gel incorporated with bile acids enhanced pharmacology of surgical implants.
Mooranian, Armin; Ionescu, Corina Mihaela; Wagle, Susbin Raj; Kovacevic, Bozica; Walker, Daniel; Jones, Melissa; Chester, Jacqueline; Johnston, Edan; Mikov, Momir; Stankov, Karmen; Elnashar, Magdy; Al-Salami, Hani.
Afiliação
  • Mooranian A; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Ionescu CM; School of Pharmacy, University of Otago, Dunedin, Otago, New Zealand.
  • Wagle SR; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Kovacevic B; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Walker D; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Jones M; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Chester J; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Johnston E; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Mikov M; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
  • Stankov K; Department of Pharmacology, Toxicology & Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Novi Sad, 21101, Serbia.
  • Elnashar M; Department of Pharmacology, Toxicology & Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Novi Sad, 21101, Serbia.
  • Al-Salami H; The Biotechnology & Drug Development Research Laboratory, Curtin Medical School & Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, Western Australia, 6102, Australia.
Ther Deliv ; 14(1): 17-29, 2023 01.
Article em En | MEDLINE | ID: mdl-36919692
In this study, we explore the delivery of insulin producing cells that may benefit those with Type 1 diabetes. Cells were delivered to mice in a protective matrix. The matrix contained unique components, such as bile acids, that allowed for sustained reduction in glucose levels. This process may represent a novel diabetes treatment that could be an alternative to traditional insulin therapies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante das Ilhotas Pancreáticas / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 Limite: Animals Idioma: En Revista: Ther Deliv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante das Ilhotas Pancreáticas / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 Limite: Animals Idioma: En Revista: Ther Deliv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália País de publicação: Reino Unido