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Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine-Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia.
Schwarz, Ute I; Woldanski-Travaglini, Morgan; Swanston, Valerie; Mikhail, Mariam; Cacciotti, Chantel; Cairney, Elizabeth; Patel, Serina; Seelisch, Jennifer; Tole, Soumitra; Wilejto, Marta; Tirona, Rommel G; Kim, Richard B; Zorzi, Alexandra P.
Afiliação
  • Schwarz UI; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Woldanski-Travaglini M; Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Swanston V; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Mikhail M; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Cacciotti C; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Cairney E; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Patel S; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Seelisch J; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Tole S; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Wilejto M; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Tirona RG; Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Kim RB; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
  • Zorzi AP; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Clin Pharmacol Ther ; 113(6): 1326-1336, 2023 06.
Article em En | MEDLINE | ID: mdl-36932910

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Mercaptopurina Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Child / Child, preschool / Humans Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Mercaptopurina Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Child / Child, preschool / Humans Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá