Modeling Alzheimer's disease in primary neurons reveals DNA damage response coupled with MAPK-DLK signaling in wild-type tau-induced neurodegeneration.

Li, Sanming; Roy, Ethan R; Wang, Yanyu; Watkins, Trent; Cao, Wei

Li, Sanming; Roy, Ethan R; Wang, Yanyu; Watkins, Trent; Cao, Wei.

Afiliação

Li S; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Roy ER; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Wang Y; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Watkins T; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA. Current address: Department of Neurology, University of California at San Francisco, San Francisco, CA 94158 USA.
Cao W; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

Res Sq ; 2023 Mar 07.

Article em En | MEDLINE | ID: mdl-36945524

Palavras-chave

Alzheimer; Axonal degeneration; DLK; DNA damage; MAP kinase; Neurodegeneration; Tauopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Res Sq Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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