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Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses.
Citarella, Andrea; Moi, Davide; Pedrini, Martina; Pérez-Peña, Helena; Pieraccini, Stefano; Dimasi, Alessandro; Stagno, Claudio; Micale, Nicola; Schirmeister, Tanja; Sibille, Giulia; Gribaudo, Giorgio; Silvani, Alessandra; Giannini, Clelia; Passarella, Daniele.
Afiliação
  • Citarella A; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Moi D; Dipartimento di Scienze Chimiche e Geologiche, Università di Cagliari, Cittadella Universitaria - S.S. 554 bivio per Sestu, 09042, Monserrato, CA, Italy. davide.moi2@gmail.com.
  • Pedrini M; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Pérez-Peña H; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Pieraccini S; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Dimasi A; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Stagno C; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Micale N; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Schirmeister T; Department of Medicinal Chemistry, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany.
  • Sibille G; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123, Torino, Italy.
  • Gribaudo G; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123, Torino, Italy.
  • Silvani A; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Giannini C; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
  • Passarella D; Department of Chemistry, University of Milan, Via Golgi 19, 20133, Milano, Italy. andrea.citarella@unimi.it.
Org Biomol Chem ; 21(18): 3811-3824, 2023 05 10.
Article em En | MEDLINE | ID: mdl-37078164
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália País de publicação: Reino Unido