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Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia.
Chen, Kun-Chi; Hsiao, I-Hsin; Huang, Yu-Nan; Chou, Yu-Tung; Lin, Yi-Chun; Hsieh, Ju-Yi; Chang, Yung-Lung; Wu, Kang-Hsi; Liu, Guang-Yaw; Hung, Hui-Chih.
Afiliação
  • Chen KC; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Hsiao IH; Ph.D. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan.
  • Huang YN; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Chou YT; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Lin YC; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Hsieh JY; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Chang YL; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
  • Wu KH; Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan.
  • Liu GY; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
  • Hung HC; Department Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.
Cell Oncol (Dordr) ; 46(5): 1301-1316, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37079187
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / NAD Limite: Animals / Humans Idioma: En Revista: Cell Oncol (Dordr) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / NAD Limite: Animals / Humans Idioma: En Revista: Cell Oncol (Dordr) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan País de publicação: Holanda