[Diagnosis of cryoglobulinemic vasculitis based on B symptoms and peripheral neuropathy: a case report].
Rinsho Shinkeigaku
; 63(5): 291-297, 2023 May 27.
Article
em Ja
| MEDLINE
| ID: mdl-37100623
ABSTRACT
A man in his 50s presented with a 2-month history of paresthesia and hypoesthesia of the extremities and B symptoms including low-grade fever, weight loss, and night sweats. He also reported a 3-year history of skin discoloration in cold weather. Laboratory test results showed a high white blood cell count and elevated serum C-reactive protein and rheumatoid factor (RF) levels. Complement levels were low, and tests for cryoglobulin showed positive results. Computed tomography revealed generalized lymphadenopathy, and 18F-fluorodeoxyglucose-positron emission tomography showed increased uptake; therefore, we performed cervical lymph node and muscle biopsies. The patient was diagnosed with nodular marginal zone lymphoma and cryoglobulinemic vasculitis (CV) and received chemotherapy and steroid treatment with improvement in symptoms. CV is a rare immune complex small-vessel vasculitis. It is important to measure RF and complement levels and consider infections, collagen diseases, and hematological disorders in the differential diagnosis in patients with suspected vasculitis or CV.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasculite
/
Doenças do Sistema Nervoso Periférico
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Crioglobulinemia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
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Male
Idioma:
Ja
Revista:
Rinsho Shinkeigaku
Ano de publicação:
2023
Tipo de documento:
Article