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Mapping intellectual structure and research hotspots in the field of fibroblast-associated DFUs: a bibliometric analysis.
Zhu, Yushu; Lu, Jianyu; Wang, Siqiao; Xu, Dayuan; Wu, Minjuan; Xian, Shuyuan; Zhang, Wei; Tong, Xirui; Liu, Yifan; Huang, Jie; Jiang, Luofeng; Guo, Xinya; Xie, Sujie; Gu, Minyi; Jin, Shuxin; Ma, Yicheng; Huang, Runzhi; Xiao, Shichu; Ji, Shizhao.
Afiliação
  • Zhu Y; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Lu J; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Wang S; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Xu D; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Wu M; School of Medicine, Tongji University, Shanghai, China.
  • Xian S; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Zhang W; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Tong X; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Liu Y; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Huang J; School of Medicine, Tongji University, Shanghai, China.
  • Jiang L; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Guo X; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Xie S; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Gu M; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Jin S; School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Ma Y; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Huang R; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
  • Xiao S; Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
  • Ji S; Research Unit of Critical Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, China.
Front Endocrinol (Lausanne) ; 14: 1109456, 2023.
Article em En | MEDLINE | ID: mdl-37124747
ABSTRACT

Background:

Diabetic foot ulcers (DFUs) are one of the most popular and severe complications of diabetes. The persistent non-healing of DFUs may eventually contribute to severe complications such as amputation, which presents patients with significant physical and psychological challenges. Fibroblasts are critical cells in wound healing and perform essential roles in all phases of wound healing. In diabetic foot patients, the disruption of fibroblast function exacerbates the non-healing of the wound. This study aimed to summarize the hotspots and evaluate the global research trends on fibroblast-related DFUs through bibliometric analysis.

Methods:

Scientific publications on the study of fibroblast-related DFUs from January 1, 2000 to April 27, 2022 were retrieved from the Web of Science Core Collection (WoSCC). Biblioshiny software was primarily performed for the visual analysis of the literature, CiteSpace software and VOSviewer software were used to validate the results.

Results:

A total of 479 articles on fibroblast-related DFUs were retrieved. The most published countries, institutions, journals, and authors in this field were the USA, The Chinese University of Hong Kong, Wound Repair and Regeneration, and Seung-Kyu Han. In addition, keyword co-occurrence networks, historical direct citation networks, thematic map, and the trend topics map summarize the research hotspots and trends in this field.

Conclusion:

Current studies indicated that research on fibroblast-related DFUs is attracting increasing concern and have clinical implications. The cellular and molecular mechanisms of the DFU pathophysiological process, the molecular mechanisms and therapeutic targets associated with DFUs angiogenesis, and the measures to promote DFUs wound healing are three worthy research hotspots in this field.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pé Diabético Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pé Diabético Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China