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Novel therapeutic strategies for recurrent SCLC.
Moliner, Laura; Zhang, Bingnan; Lamberti, Giuseppe; Ardizzoni, Andrea; Byers, Lauren A; Califano, Raffaele.
Afiliação
  • Moliner L; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester M20 4BX, UK.
  • Zhang B; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Lamberti G; Department of Specialized, Experimental and Diagnostic Medicine, University of Bologna, Bologna 40138, Italy.
  • Ardizzoni A; Department of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
  • Byers LA; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Califano R; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester M20 4BX, UK; Division of Cancer Sciences, The University of Manchester, Manchester M13 9NT, UK. Electronic address: raffaele.califano@nhs.net.
Crit Rev Oncol Hematol ; 186: 104017, 2023 Jun.
Article em En | MEDLINE | ID: mdl-37150311
ABSTRACT
Therapeutic options for patients with relapsed SCLC are limited, and the prognosis in this setting remains poor. While clinical outcomes for frontline treatment have modestly improved with the introduction of immunotherapy, treatment in the second-line setting persists almost unchanged. In this review, current treatment options and recent advances in molecular biology are described. Emerging therapeutic options in this setting, and potential strategies to improve clinical outcomes of these patients are also addressed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Pequenas Células do Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Crit Rev Oncol Hematol Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Pequenas Células do Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Crit Rev Oncol Hematol Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido