Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors.

Dai, Zhen; Liu, Wan-Cong; Chen, Xiao-Yi; Wang, Xiao; Li, Jun-Long; Zhang, Xiang

Dai, Zhen; Liu, Wan-Cong; Chen, Xiao-Yi; Wang, Xiao; Li, Jun-Long; Zhang, Xiang.

Afiliação

Dai Z; Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, China.
Liu WC; Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, China.
Chen XY; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.
Wang X; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China.
Li JL; Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, China.
Zhang X; Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, China.

Front Immunol ; 14: 1178662, 2023.

Article em En | MEDLINE | ID: mdl-37275856

Assuntos

COVID-19; Piroptose; Humanos; Gasderminas; Inflamassomos/metabolismo; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo

Palavras-chave

GSDMD; GSDMD inhibitors; GSDMD pores; inflammasome; mechanism; pyroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piroptose / COVID-19 Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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