Mechanochemical Rhodium-Catalyzed C-H Bond Amidation of Ferrocenes by Ball Milling.
Chem Asian J
; 18(14): e202300330, 2023 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-37300365
ABSTRACT
A direct protocol for Rh-catalyzed C-H amidation of ferrocenes in a ball mill using dioxazolones as the amide source under solvent-free conditions was developed. The corresponding ortho-aminated products were formed in 3â
hours and the yields were up to 99% in the absence of base. This method could be a typically sustainable and environmental-friendly alternative method to traditional methodologies, with the advantages of wide substrate range, good functional group tolerance and gram-scale synthesis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Asian J
Ano de publicação:
2023
Tipo de documento:
Article