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Outbreaks by Klebsiella oxytoca in neonatal intensive care units: Analysis of an outbreak in a tertiary hospital and systematic review.
Liébana-Rodríguez, María; Recacha-Villamor, Esther; Díaz-Molina, Carmen; Pérez-Palacios, Patricia; Martín-Hita, Lina; Enríquez-Maroto, Francisca; Gutiérrez-Fernández, José.
Afiliação
  • Liébana-Rodríguez M; Departamento de Medicina Preventiva y Salud Pública, Hospital Virgen de las Nieves. Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain.
  • Recacha-Villamor E; Unidad de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain.
  • Díaz-Molina C; Departamento de Medicina Preventiva y Salud Pública, Hospital Virgen de las Nieves. Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain.
  • Pérez-Palacios P; Unidad de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain.
  • Martín-Hita L; Departamento de Microbiología. Hospital Virgen de las Nieves, Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain.
  • Enríquez-Maroto F; Departamento de Medicina Preventiva y Salud Pública, Hospital Virgen de las Nieves. Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain.
  • Gutiérrez-Fernández J; Departamento de Microbiología. Hospital Virgen de las Nieves, Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain; Departamento de Microbiología, Universidad de Granada-Instituto de Investigación Biosanitaria de Granada, Ibs-Granada, Granada, Spain. Electronic address: jo
Article em En | MEDLINE | ID: mdl-37328344
OBJECTIVE: Klebsiella oxytoca can cause nosocomial infections, affecting vulnerable newborns. There are few studies describing nosocomial outbreaks in the neonatal intensive care units (NICU). In this study, a systematic review of the literature was carried out to know the main characteristics of these outbreaks and the evolution of one is described. METHODS: We conducted a systematic review in the Medline database up to July 2022, and present a descriptive study of an outbreak with 21 episodes in the NICU of a tertiary hospital, between September 2021 and January 2022. RESULTS: 9 articles met the inclusion criteria. The duration of outbreaks was found to be variable, of which 4 (44.4%) lasted for a year or more. Colonization (69%) was more frequent than infections (31%) and the mortality rate was 22.4%. In studies describing sources, the most frequent was the environmental origin (57.1%). In our outbreak there were 15 colonizations and 6 infections. The infections were mild conjunctivitis without sequelae. Molecular typing analysis made it possible to detect 4 different clusters. CONCLUSIONS: There is an important variability in the evolution and results of the published outbreaks, highlighting a greater number of colonized, use of PFGE (pulsed-field gel electrophoresis) techniques for molecular typing and implementation of control measures. Finally, we describe an outbreak in which 21 neonates were affected with mild infections, resolved without sequelae and whose control measures were effective.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Systematic_reviews Idioma: En Revista: Enferm Infecc Microbiol Clin (Engl Ed) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Systematic_reviews Idioma: En Revista: Enferm Infecc Microbiol Clin (Engl Ed) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha País de publicação: Espanha