[Research of progress of mitochondria in the pathogenesis of sepsis].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
; 35(6): 669-672, 2023 Jun.
Article
em Zh
| MEDLINE
| ID: mdl-37366138
ABSTRACT
Sepsis is an organ dysfunction caused by dysregulation of the body's response to infection, with high morbidity and mortality. The pathogenesis of sepsis is still unclear, and there are no specific treatment drugs. As a cell energy supply unit, the dynamic changes of mitochondria are closely related to various diseases. Studies have shown that structure and function of mitochondria are changed in different organs during sepsis. The energy shortage, oxidative stress change, imbalance of fusion and fission, autophagy reduce, biological functions of mitochondria play important roles in sepsis progress, which can provide a research target for the treatment of sepsis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sepse
/
Mitocôndrias
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
Zh
Revista:
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Ano de publicação:
2023
Tipo de documento:
Article
País de publicação:
CHINA
/
CN
/
REPUBLIC OF CHINA