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Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia.
Wu, Yue; Zhang, Linjian; Sun, Zhuoli; Qiu, Xusheng; Chen, Yafen; Su, Kaijun; Yang, Le; Du, Zhongqiu; Dong, Ying; Yang, Fulai; Li, Xiang; Zhang, Xiaojin.
Afiliação
  • Wu Y; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Zhang L; Department of Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Sun Z; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Qiu X; Department of Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Chen Y; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Su K; Department of Pharmaceutical Engineering, China Pharmaceutical University, Nanjing 211198, China.
  • Yang L; Department of Orthopedics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
  • Du Z; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Dong Y; Department of Pharmaceutical Engineering, China Pharmaceutical University, Nanjing 211198, China.
  • Yang F; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Li X; Department of Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Zhang X; State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
J Med Chem ; 66(13): 8545-8563, 2023 07 13.
Article em En | MEDLINE | ID: mdl-37367818
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Prolil-Hidrolase / Anemia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Prolil-Hidrolase / Anemia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos