Functional analysis of the <i>Aspergillus fumigatus</i> kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target.

van Rhijn, Norman; Zhao, Can; Al-Furaji, Narjes; Storer, Isabelle; Valero, Clara; Gago, Sara; Chown, Harry; Baldin, Clara; Fortune-Grant, Rachael; Shuraym, Hajer Bin; Ivanova, Lia; Kniemeyer, Olaf; Krüger, Thomas; Bignell, Elaine; Goldman, Gustavo; Amich, Jorge; Delneri, Daniela; Bowyer, Paul; Brakhage, Axel; Haas, Hubertus; Bromley, Michael

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target.

van Rhijn, Norman; Zhao, Can; Al-Furaji, Narjes; Storer, Isabelle; Valero, Clara; Gago, Sara; Chown, Harry; Baldin, Clara; Fortune-Grant, Rachael; Shuraym, Hajer Bin; Ivanova, Lia; Kniemeyer, Olaf; Krüger, Thomas; Bignell, Elaine; Goldman, Gustavo; Amich, Jorge; Delneri, Daniela; Bowyer, Paul; Brakhage, Axel; Haas, Hubertus; Bromley, Michael.

Afiliação

van Rhijn N; University of Manchester.
Zhao C; Manchester Fungal Infection Group.
Al-Furaji N; Manchester Fungal Infection Group.
Storer I; University of Manchester.
Valero C; Manchester Fungal Infection Group.
Gago S; University of Manchester.
Chown H; University of Manchester.
Baldin C; Innsbruck Medical University.
Fortune-Grant R; Manchester Fungal Infection Group.
Shuraym HB; Manchester Fungal Infection Group.
Ivanova L; Leibniz Institute for Natural Product Research and Infection Biology.
Kniemeyer O; Leibniz Institute for Natural Product Research and Infection Biology.
Krüger T; Leibniz Institute for Natural Product Research and Infection Biology.
Bignell E; Manchester Fungal Infection Group.
Goldman G; Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Bloco Q, Universidade de São Paulo.
Amich J; Instituto de Salud Carlos III.
Delneri D; University of Manchester.
Bowyer P; University of Manchester.
Brakhage A; Leibniz Institute for Natural Product Research and Infection Biology - University of Jena.
Haas H; Institute of Molecular Biology/Biocenter, Innsbruck Medical University.
Bromley M; University of Manchester.

Res Sq ; 2023 May 30.

Article em En | MEDLINE | ID: mdl-37398159

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Res Sq Ano de publicação: 2023 Tipo de documento: Article