Direct Effects of Toxic Divalent Cations on Contractile Proteins with Implications for the Heart: Unraveling Mechanisms of Dysfunction.

Gerzen, Oksana P; Votinova, Veronika O; Potoskueva, Iulia K; Tzybina, Alyona E; Nikitina, Larisa V

Gerzen, Oksana P; Votinova, Veronika O; Potoskueva, Iulia K; Tzybina, Alyona E; Nikitina, Larisa V.

Afiliação

Gerzen OP; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, 620049 Ekaterinburg, Russia.
Votinova VO; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, 620049 Ekaterinburg, Russia.
Potoskueva IK; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, 620049 Ekaterinburg, Russia.
Tzybina AE; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, 620049 Ekaterinburg, Russia.
Nikitina LV; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, 620049 Ekaterinburg, Russia.

Int J Mol Sci ; 24(13)2023 Jun 24.

Article em En | MEDLINE | ID: mdl-37445756

Assuntos

Proteínas Contráteis; Coração; Cátions Bivalentes/farmacologia; Miosinas/metabolismo; Cátions; Cálcio/farmacologia

Palavras-chave

ATPase activity; EF-hand proteins; cardiotoxicity; divalent cations; heart muscle; myosin; regulatory light chain; toxic ions; troponin C

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Contráteis / Coração Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Suíça

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