Immune Reconstitution Inflammatory Syndrome and Drug-Induced Liver Injury During Treatment of Disseminated Tuberculosis in a Liver Transplant Recipient: A Case Report.
Transplant Proc
; 55(8): 1972-1974, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-37468353
Studies have shown that tuberculosis (TB) incidence is 20 to 70 times higher in solid organ transplantation recipients. Immunosuppression makes transplant recipients more vulnerable to infection and can interfere with the treatment. Our case report describes a patient who experienced immune reconstitution inflammatory syndrome (IRIS) and drug-induced liver injury (DILI) related to TB medications for disseminated pulmonary and hepatic TB. In addition to anti-TB medication, the patient received a high-dose steroid for IRIS and a change of anti-TB medication to a secondary regimen for DILI. This case illustrates various responses to anti-TB treatment in a liver transplant recipient and the necessity of closely monitoring immune suppression and liver function.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Miliar
/
Transplante de Fígado
/
Síndrome Inflamatória da Reconstituição Imune
/
Doença Hepática Induzida por Substâncias e Drogas
Limite:
Humans
Idioma:
En
Revista:
Transplant Proc
Ano de publicação:
2023
Tipo de documento:
Article
País de publicação:
Estados Unidos