Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1&#945; and hypoxia-inducible factor-2&#945; signaling and benefits chondrocytes.

Wang, Pengzhen; Zhu, Pingping; Zhang, Shaoheng; Yuan, Wei; Liu, Zhihe

Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1α and hypoxia-inducible factor-2α signaling and benefits chondrocytes.

Wang, Pengzhen; Zhu, Pingping; Zhang, Shaoheng; Yuan, Wei; Liu, Zhihe.

Afiliação

Wang P; Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Zhu P; Department of Neurology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, Guangdong, China.
Zhang S; Department of Cardiology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Yuan W; Department of Hepatobiliary Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, Guangdong.
Liu Z; Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.

PeerJ ; 11: e15917, 2023.

Article em En | MEDLINE | ID: mdl-37637163

Assuntos

Condrócitos; Subunidade alfa do Fator 1 Induzível por Hipóxia; Animais; Camundongos; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Metaloproteinase 9 da Matriz; Hipóxia

Palavras-chave

Chondrocytes; Extracellular matrix (ECM); Far upstream element binding protein 1 (FUBP1); Hypoxia-inducible factor-1/2α (HIF-1/2α); Icariin (ICA)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Condrócitos / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Animals Idioma: En Revista: PeerJ Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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