Enhanced transscleral delivery using superficial ultrasound exposure and drug-loaded hydrogel.

Hu, Yaxin; Weng, Weixiong; Zhang, Yuxi; Zhu, Ying; Zhang, Xinyu

Hu, Yaxin; Weng, Weixiong; Zhang, Yuxi; Zhu, Ying; Zhang, Xinyu.

Afiliação

Hu Y; School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, Guangdong 518055, China.
Weng W; School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, Guangdong 518055, China.
Zhang Y; School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, Guangdong 518055, China.
Zhu Y; School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, Guangdong 518055, China.
Zhang X; School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China; National-regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, Guangdong 518055, China. Electronic address: xyzhang9@szu.edu.c

Int J Pharm ; 645: 123359, 2023 Oct 15.

Article em En | MEDLINE | ID: mdl-37652279

Assuntos

Hidrogéis; Segmento Posterior do Olho; Animais; Coelhos; Suínos; Permeabilidade; Esclera; Ultrassonografia; Sistemas de Liberação de Medicamentos/métodos

Palavras-chave

Acoustic adaptor; Delivery efficiency; Dual-crosslinked hydrogel; Penetration depth; Ultrasound-triggered release

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis / Segmento Posterior do Olho Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Int J Pharm Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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