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A thorough and current study of miR-214-related targets in cancer.
Sukmana, Bayu Indra; Al-Hawary, Sulieman Ibraheem Shelash; Abosaooda, Munther; Adile, Mohaned; Gupta, Reena; Saleh, Ebraheem Abdu Musad; Alwaily, Enas R; Alsaab, Hashem O; Sapaev, I B; Mustafa, Yasser Fakri.
Afiliação
  • Sukmana BI; Departement of Oral Biology, Lambung Mangkurat University, Banjarmasin, Indonesia.
  • Al-Hawary SIS; Department of Business Administration, Business School, Al al-Bayt University, P.O.BOX 130040, Mafraq 25113, Jordan.
  • Abosaooda M; College of Pharmacy, The Islamic University, 54001 Najaf, Iraq.
  • Adile M; Medical Technical College, Al-Farahidi University, Baghdad, Iraq.
  • Gupta R; Institute of Pharmaceutical Research, GLA University, District-Mathura, Uttar Pradesh 281406, India. Electronic address: rspg80@gmail.com.
  • Saleh EAM; Department of Chemistry, Prince Sattam Bin Abdulaziz University, College of Arts and Science, Wadi Al-Dawasir 11991, Saudi Arabia.
  • Alwaily ER; Microbiology Research Group, College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq.
  • Alsaab HO; Pharmaceutics and Pharmaceutical Technology, Taif University, Taif, Saudi Arabia.
  • Sapaev IB; Tashkent Institute of Irrigation and Agricultural Mechanization Engineers" National Research University, Tashkent, Uzbekistan; New Uzbekistan University, Tashkent, Uzbekistan.
  • Mustafa YF; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul 41001, Iraq.
Pathol Res Pract ; 249: 154770, 2023 Sep.
Article em En | MEDLINE | ID: mdl-37660658
Cancer is a complex genetic anomaly involving coding and non-coding transcript structural and expressive irregularities. A class of tiny non-coding RNAs known as microRNAs (miRNAs) regulates gene expression at the post-transcriptional level by binding only to messenger RNAs (mRNAs). Due to their capacity to target numerous genes, miRNAs have the potential to play a significant role in the development of tumors by controlling several biological processes, including angiogenesis, drug resistance, metastasis, apoptosis, proliferation, and drug resistance. According to several recent studies, miRNA-214 has been linked to the emergence and spread of tumors. The human genome's q24.3 arm contains the DNM3 gene, which is about 6 kb away and includes the microRNA-214. Its primary purpose was the induction of apoptosis in cancerous cells. The multifaceted and complex functions of miR-214 as a modulator in neoplastic conditions have been outlined in the current review.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Neoplasias Limite: Humans Idioma: En Revista: Pathol Res Pract Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Indonésia País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Neoplasias Limite: Humans Idioma: En Revista: Pathol Res Pract Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Indonésia País de publicação: Alemanha