Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels.

Yokoyama, Koji; Yakuo, Toshinari; Mamada, Mitsukazu; Nagata, Masashi

Yokoyama, Koji; Yakuo, Toshinari; Mamada, Mitsukazu; Nagata, Masashi.

Afiliação

Yokoyama K; Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Yakuo T; Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Mamada M; Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Nagata M; Department of Pharmacy, Tokyo Medical and Dental University Hospital, Tokyo, JPN.

Cureus ; 15(8): e43002, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37671213

ABSTRACT

ABSTRACT

The antipsychotic olanzapine is used increasingly to treat various psychiatric illnesses. Accidental olanzapine overdose is uncommon among children. Here, we report a case of a child presenting with an unexplained coma. Accidental ingestion of olanzapine (20 mg) was confirmed by measurement of drug concentrations in both serum and plasma.

Palavras-chave

blood concentration measurement; impaired consciousness; olanzapine; proper specimen storage; toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cureus Ano de publicação: 2023 Tipo de documento: Article