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Complete surgical revascularization after NSTEMI and unstable angina in patients with multivessel coronary artery disease: Institutional experience.
Kaya, Ibrahim C; Bulut, Halil I; Candelario, Katherine; Ozbayburtlu, Merih; Balkanay, Ozan O.
Afiliação
  • Kaya IC; Department of Cardiovascular Surgery, Eskisehir City Health Practice and Research Centers, Eskisehir, Turkey.
  • Bulut HI; Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Candelario K; Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
  • Ozbayburtlu M; Department of Cardiovascular Surgery, Eskisehir City Health Practice and Research Centers, Eskisehir, Turkey.
  • Balkanay OO; Department of Cardiovascular Surgery, Cerrahpasa School of Medicine, Istanbul University Cerrahpasa, Istanbul, Turkey.
Asian Cardiovasc Thorac Ann ; 31(8): 675-681, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37671414
ABSTRACT

INTRODUCTION:

The feasibility and standardization of coronary artery bypass grafting (CABG) in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) and unstable angina (UA) remain topics of ongoing debate. In this study, feasibility and early-term outcomes of CABG in patients with NSTE-ACS and UA were discussed.

METHODS:

This study enrolled 79 patients who underwent on-pump CABG with complete revascularization between January 2020 and May 2022. the survival rates analyzed using Kaplan Meier test with log rank test. The p value of statistical significance was taken as below 0.05.

RESULTS:

Preoperatively, the patients had a mean age of 60.9 years and a BMI of 28.0. The medical history included hypertension (50.6%), peripheral arterial disease and atrial fibrillation (12.7%), and other comorbidities such as COPD (22.8%) and type 2 diabetes mellitus (44.3%). Intraoperatively, the mean distal anastomosis count was 3.4, with average cardiopulmonary bypass and aortic cross-clamp times of 84.0 and 49.0 min, respectively. Early-term outcomes revealed low rates of mortality (2.5%) and complications such as myocardial infarction (1.3%), acute kidney injury (5.1%) and transient ischemic attack (5.1%). Post-discharge outcomes demonstrated low cardiac and all-cause mortality rates (2.5% and 3.8%, respectively) and a high overall survival rate (93.7%) at 12-month follow-up.

CONCLUSION:

This study demonstrated the feasibility and positive outcomes of complete surgical revascularization in patients with UA and NSTE-ACS. It showed no graft occlusion or stroke, low complication rates and promising survival outcomes. Further research is needed for confirmation and to establish the procedure's efficacy and safety in this patient population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Diabetes Mellitus Tipo 2 / Síndrome Coronariana Aguda / Infarto do Miocárdio sem Supradesnível do Segmento ST Tipo de estudo: Etiology_studies Limite: Humans / Middle aged Idioma: En Revista: Asian Cardiovasc Thorac Ann Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Turquia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Diabetes Mellitus Tipo 2 / Síndrome Coronariana Aguda / Infarto do Miocárdio sem Supradesnível do Segmento ST Tipo de estudo: Etiology_studies Limite: Humans / Middle aged Idioma: En Revista: Asian Cardiovasc Thorac Ann Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Turquia