Cytomegalovirus Viral Load Threshold to Guide Preemptive Therapy in Hematopoietic Cell Transplant Recipients: Correlation with CMV Disease.

Sadowska-Klasa, Alicja; Leisenring, Wendy M; Limaye, Ajit P; Boeckh, Michael

Sadowska-Klasa, Alicja; Leisenring, Wendy M; Limaye, Ajit P; Boeckh, Michael.

Afiliação

Sadowska-Klasa A; Fred Hutchinson Cancer Center, Seattle, WA.
Leisenring WM; Medical University of Gdansk, Department of Hematology and Transplantology, Poland.
Limaye AP; Fred Hutchinson Cancer Center, Seattle, WA.
Boeckh M; Fred Hutchinson Cancer Center, Seattle, WA.

J Infect Dis ; 2023 Sep 08.

Article em En | MEDLINE | ID: mdl-37682870

ABSTRACT

ABSTRACT

A systematic review of recent randomized and observational studies demonstrated that antiviral preemptive therapy started at cytomegalovirus (CMV) viral load thresholds between 2 and 3 log10 IU/mL were associated with similar CMV disease rates. Thus, viral thresholds in this range appear to effectively protect patients not receiving prophylaxis.

Palavras-chave

CMV; CMV disease; PET; review; viral load threshold

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Observational_studies Idioma: En Revista: J Infect Dis Ano de publicação: 2023 Tipo de documento: Article

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