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TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.
Wu, Gongwei; Yoshida, Noriaki; Liu, Jihe; Zhang, Xiaoyang; Xiong, Yuan; Heavican-Foral, Tayla B; Mandato, Elisa; Liu, Huiyun; Nelson, Geoffrey M; Yang, Lu; Chen, Renee; Donovan, Katherine A; Jones, Marcus K; Roshal, Mikhail; Zhang, Yanming; Xu, Ran; Nirmal, Ajit J; Jain, Salvia; Leahy, Catharine; Jones, Kristen L; Stevenson, Kristen E; Galasso, Natasha; Ganesan, Nivetha; Chang, Tiffany; Wu, Wen-Chao; Louissaint, Abner; Debaize, Lydie; Yoon, Hojong; Dal Cin, Paola; Chan, Wing C; Ho Sui, Shannan J; Ng, Samuel Y; Feldman, Andrew L; Horwitz, Steven M; Adelman, Karen; Fischer, Eric S; Chen, Chun-Wei; Weinstock, David M; Brown, Myles.
Afiliação
  • Wu G; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Yoshida N; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Liu J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Zhang X; Harvard Chan Bioinformatics Core, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
  • Xiong Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Heavican-Foral TB; Broad Institute of MIT and Harvard University, Cambridge, MA 02142, USA.
  • Mandato E; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.
  • Liu H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Nelson GM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Yang L; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Chen R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Donovan KA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Jones MK; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Roshal M; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
  • Zhang Y; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA 91016, USA.
  • Xu R; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA 91016, USA.
  • Nirmal AJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Jain S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Leahy C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Jones KL; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Stevenson KE; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Galasso N; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Ganesan N; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Chang T; Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.
  • Wu WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Louissaint A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Debaize L; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Yoon H; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Dal Cin P; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Chan WC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Ho Sui SJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Ng SY; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Feldman AL; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Horwitz SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Adelman K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Fischer ES; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Chen CW; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Weinstock DM; Department of Pathology, City of Hope Medical Center, Duarte, CA 91010, USA.
  • Brown M; Harvard Chan Bioinformatics Core, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Sci Transl Med ; 15(714): eadi7244, 2023 09 20.
Article em En | MEDLINE | ID: mdl-37729434
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Núcleo Celular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Núcleo Celular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos