Regulatory architecture of cell identity genes and housekeeping genes.
Trends Cell Biol
; 33(12): 1010-1013, 2023 12.
Article
em En
| MEDLINE
| ID: mdl-37775397
ABSTRACT
Gene regulation and chromosome architecture are intimately linked. Genes with prominent roles in cell identity are often regulated by clusters of enhancer elements. By contrast, a recent study shows housekeeping genes are often regulated through clustering of promoters. We discuss here new regulatory insights for these two types of genes.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Elementos Facilitadores Genéticos
/
Genes Essenciais
Limite:
Humans
Idioma:
En
Revista:
Trends Cell Biol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos