Frequency and burden of disease for SARS-CoV-2 and other viral respiratory tract infections in children under the age of 2 months.
Pediatr Pulmonol
; 59(1): 101-110, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-37795812
ABSTRACT
OBJECTIVE:
To evaluate the frequency and burden of disease of SARS-CoV-2 and other respiratory viruses in children under the age of 2 months.METHODS:
A retrospective, cross-sectional, single-center study was conducted between March 2021 and February 2022. All children under the age of 2 months and tested for SARS-CoV-2 were included. The frequency of SARS-CoV-2, of other respiratory viruses and the burden of disease caused by SARS-CoV-2 and other respiratory viruses were evaluated.RESULTS:
Seven hundred and twenty-seven children with an RT-PCR test for SARS-CoV-2 were included (mean age 0.9 months (±0.6); boys 57%); 514 (71%) in the emergency room and 213 (29%) in hospital. Among them, 62 (8.5%) had a positive RT-PCR test for SARS-CoV-2, more often in the Omicron period (23%) than in the Alpha period (4%). Of the 565 (78%) with a multiplex RT-PCR test for other viruses, 325 (58%) were positive. Children with a positive SARS-CoV-2 were less likely to have required respiratory support (p = 0.001), enteral nutrition (p = 0.03), or intensive care admission (p = 0.01) and had a shorter hospital stay than children with other respiratory viruses (5 days vs. 7 days, p = 0.007).CONCLUSION:
In this young population of children, SARS-CoV-2 infection was less frequent and less severe than other viral respiratory infections.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
/
COVID-19
Limite:
Child
/
Humans
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Infant
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Male
/
Newborn
Idioma:
En
Revista:
Pediatr Pulmonol
Assunto da revista:
PEDIATRIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
França