RANK-L inhibitor as a promising agent for refractory extensive craniofacial fibrous dysplasia: A case report.
Head Neck
; 46(1): E1-E5, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-37823398
ABSTRACT
BACKGROUND:
McCune-Albright syndrome is a rare disorder characterized by polyostotic fibrous dysplasia (FD), café-au-lait skin pigmentation, and endocrine dysfunction. Extensive FD in the craniofacial region can present significant challenges in terms of disease control and carries a high risk of permanent visual impairment.METHODS:
We present a case of medically and surgically resistant FD that required nine optic nerve decompressions.RESULTS:
The condition was ultimately controlled with the use of the denosumab agent.CONCLUSION:
The case highlights the importance and potential efficacy of denosumab in resistant FD management, particularly in cases involving sensitive organs.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Displasia Fibrosa Poliostótica
/
Displasia Fibrosa Craniofacial
Limite:
Humans
Idioma:
En
Revista:
Head Neck
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Egito
País de publicação:
Estados Unidos