Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity.

Farias Amorim, Camila; Lovins, Victoria M; Singh, Tej Pratap; Novais, Fernanda O; Harris, Jordan C; Lago, Alexsandro S; Carvalho, Lucas P; Carvalho, Edgar M; Beiting, Daniel P; Scott, Phillip; Grice, Elizabeth A

Farias Amorim, Camila; Lovins, Victoria M; Singh, Tej Pratap; Novais, Fernanda O; Harris, Jordan C; Lago, Alexsandro S; Carvalho, Lucas P; Carvalho, Edgar M; Beiting, Daniel P; Scott, Phillip; Grice, Elizabeth A.

Afiliação

Farias Amorim C; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lovins VM; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Singh TP; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Novais FO; Department of Microbial Infection and Immunity, College of Medicine, Ohio State University, Columbus, OH 43210, USA.
Harris JC; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lago AS; Laboratório de Pesquisas Clínicas do Instituto de Pesquisas Gonçalo Muniz-Fiocruz, Salvador, Bahia 40296-710, Brazil.
Carvalho LP; Laboratório de Pesquisas Clínicas do Instituto de Pesquisas Gonçalo Muniz-Fiocruz, Salvador, Bahia 40296-710, Brazil.
Carvalho EM; Immunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia 40110-060, Brazil.
Beiting DP; Laboratório de Pesquisas Clínicas do Instituto de Pesquisas Gonçalo Muniz-Fiocruz, Salvador, Bahia 40296-710, Brazil.
Scott P; Immunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia 40110-060, Brazil.
Grice EA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Sci Transl Med ; 15(718): eadh1469, 2023 10 18.

Article em En | MEDLINE | ID: mdl-37851822

Assuntos

Leishmaniose Cutânea; Microbiota; Humanos; Camundongos; Animais; Staphylococcus aureus; Multiômica; Inflamação; Bactérias; Gravidade do Paciente

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Cutânea / Microbiota Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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