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Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Tiruppathi, Chinnaswamy; Wang, Dong-Mei; Ansari, Mohammad Owais; Bano, Shabana; Tsukasaki, Yoshikazu; Mukhopadhyay, Amitabha; Joshi, Jagdish C; Loch, Christian; Niessen, Hans W M; Malik, Asrar B.
Afiliação
  • Tiruppathi C; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA. tiruc@uic.edu.
  • Wang DM; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Ansari MO; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Bano S; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Tsukasaki Y; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Mukhopadhyay A; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Joshi JC; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA.
  • Loch C; AVMBioMed, King of Prussia, PA, USA.
  • Niessen HWM; Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands.
  • Malik AB; Department of Pharmacology and Regenerative Medicine and The Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL, USA. abmalik@uic.edu.
Nat Commun ; 14(1): 6582, 2023 10 18.
Article em En | MEDLINE | ID: mdl-37852964

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Junções Aderentes / Ubiquitina Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Junções Aderentes / Ubiquitina Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido