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Relationship Between Epicardial Adipose Tissue Volume and Recurrence After Ablation in Premature Ventricular Complexes.
Wang, Zhe; Li, Jiaju; Chen, Jiawei; Guo, Hehe; He, Haoming; Jiao, Siqi; Chen, Yingwei; Dong, Jianzeng; Sun, Yihong.
Afiliação
  • Wang Z; Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences and Peking Union Medical College.
  • Li J; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University.
  • Chen J; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University.
  • Guo H; Department of Radiology, The First Affiliated Hospital of Zhengzhou University.
  • He H; Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences and Peking Union Medical College.
  • Jiao S; Department of Cardiology, Peking University China-Japan Friendship School of Clinical Medicine.
  • Chen Y; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University.
  • Dong J; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University.
  • Sun Y; Department of Cardiology, Anzhen Hospital Affiliated to Capital Medical University.
Circ J ; 2023 Nov 01.
Article em En | MEDLINE | ID: mdl-37914274
BACKGROUND: Epicardial adipose tissue (EAT) is recognized as a clinical diagnostic marker for cardiometabolic disease. Thicker EAT may be associated with recurrence of ventricular tachycardia after ablation. The association between EAT volume and recurrence of premature ventricular complexes (PVC) following ablation has not been clarified. We investigated the association between EAT volume and PVC recurrence following radiofrequency catheter ablation.Methods and Results: This retrospective study included 401 patients with PVC undergoing catheter ablation with preprocedural non-contrast computed tomography between 2017 and 2022. The impact of EAT volume in predicting PVC recurrence after ablation was analyzed. The mean (±SD) age of patients was 50.2±13.3 years. Multivariable Cox analysis revealed that a large EAT volume was an independent predictor of PVC recurrence after ablation during a median follow-up of 16.3 months. Kaplan-Meier analysis showed a difference in postablation PVC recurrence between the 2 groups dichotomized around the EAT volume cut-off. The risk of recurrence increased with increasing EAT volume according to restricted cubic spline regression. Furthermore, PVC originating from epicardial locations had larger EAT volumes than those originating from the right ventricular outflow tract. CONCLUSIONS: A large EAT volume was independently associated with PVC recurrence following ablation. Patients with PVC originating from epicardial sites had large EAT volumes. EAT volume may help stratify patients according to their risk of PVC recurrence after ablation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Circ J Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Japão