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Mouse TMC4 is involved in the detection of chloride taste of salts.
Narukawa, Masataka; Masago, Aya; Murata, Momo; Saito, Yoshikazu; Kasahara, Yoichi; Abe, Keiko; Asakura, Tomiko.
Afiliação
  • Narukawa M; Department of Food and Nutrition, Kyoto Women's University , Kyoto City, Kyoto, Japan.
  • Masago A; Department of Food and Nutrition, Kyoto Women's University , Kyoto City, Kyoto, Japan.
  • Murata M; Department of Food and Nutrition, Kyoto Women's University , Kyoto City, Kyoto, Japan.
  • Saito Y; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo , Bunkyo City, Tokyo, Japan.
  • Kasahara Y; Research Department, Toyo Institute of Food Technology , Kawanishi City, Hyogo, Japan.
  • Abe K; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo , Bunkyo City, Tokyo, Japan.
  • Asakura T; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo , Bunkyo City, Tokyo, Japan.
Biosci Biotechnol Biochem ; 88(2): 203-205, 2024 Jan 24.
Article em En | MEDLINE | ID: mdl-37947260
ABSTRACT
Licking behavior with various salts in transmembrane channel-like 4 (Tmc4) knockout (KO) mice was observed. In Tmc4 KO mice, a significant decrease in sensitivity to chloride salts, such as NaCl, KCl, and NH4Cl, was observed, while no significant decrease in sensitivity to Na-gluconate was observed. This finding suggests that TMC4 may be involved in the detection of chloride taste.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sais / Cloretos Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sais / Cloretos Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão