Your browser doesn't support javascript.
loading
Extent of thyroidectomy and paratracheal lymph node dissection in total pharyngolaryngectomy for pyriform sinus cancer, and recurrence, survival, and postoperative hypoparathyroidism: A multicenter retrospective study.
Ariizumi, Yosuke; Hanai, Nobuhiro; Asakage, Takahiro; Seto, Akira; Tomioka, Toshifumi; Miyabe, Junji; Kessoku, Hisashi; Mukaigawa, Takashi; Omura, Go; Teshima, Masanori; Nishikawa, Daisuke; Saito, Yuki; Asada, Yukinori; Fujisawa, Takuo; Makino, Takuma; Nishino, Hiroshi; Sano, Daisuke; Nakahira, Mitsuhiko; Tokashiki, Kunihiko; Uemura, Hirokazu; Ueda, Tsutomu; Sakai, Akihiro; Masuda, Muneyuki; Tsujikawa, Takahiro; Hiei, Yusuke; Nishio, Naoki; Matsui, Hidetoshi; Kiyota, Naomi; Homma, Akihiro.
Afiliação
  • Ariizumi Y; Department of Head and Neck Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
  • Hanai N; Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Asakage T; Department of Head and Neck Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
  • Seto A; Division of Head and Neck, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Tomioka T; Department of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa, Japan.
  • Miyabe J; Department of Head and Neck Surgery, Osaka International Cancer Institute, Osaka, Japan.
  • Kessoku H; Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.
  • Mukaigawa T; Division of Head and Neck Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
  • Omura G; Department of Head and Neck Surgery, National Cancer Center Hospital, Tokyo, Japan.
  • Teshima M; Department of Otolaryngology - Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
  • Nishikawa D; Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Saito Y; Department of Otolaryngology - Head and Neck Surgery, University of Tokyo, Tokyo, Japan.
  • Asada Y; Department of Head and Neck Surgery, Miyagi Cancer Center, Natori, Japan.
  • Fujisawa T; Department of Otorhinolaryngology - Head and Neck Surgery, Kansai Medical University, Osaka, Japan.
  • Makino T; Department of Otolaryngology - Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
  • Nishino H; Otolaryngology Head and Neck Surgery, Jichi Medical University, Shimotsuke City, Japan.
  • Sano D; Department of Otorhinolaryngology - Head and Neck Surgery, Yokohama City University School of Medicine, Yokohama, Japan.
  • Nakahira M; Department of Head Neck Surgery, Saitama Medical University International Medical Cancer, Saitama, Japan.
  • Tokashiki K; Department of Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.
  • Uemura H; Department of Otolaryngology - Head and Neck Surgery, Nara Medical University, Kashihara, Japan.
  • Ueda T; Department of Otorhinolaryngology - Head and Neck Surgery, Hiroshima University Hospital, Hiroshima, Japan.
  • Sakai A; Department of Otolaryngology - Head and Neck Surgery, Tokai University, Isehara, Japan.
  • Masuda M; Department of Head and Neck Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
  • Tsujikawa T; Department of Otolaryngology - Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Hiei Y; Department of Otolaryngology - Head and Neck Surgery, School of Medicine, Fujita Health University, Toyoake, Japan.
  • Nishio N; Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Matsui H; Department of Head and Neck Surgery, Hyogo Cancer Center, Akashi, Japan.
  • Kiyota N; Department of Medical Oncology and Hematology, Kobe University Hospital, Kobe, Japan.
  • Homma A; Department of Otolaryngology - Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Head Neck ; 46(2): 269-281, 2024 Feb.
Article em En | MEDLINE | ID: mdl-37955187
ABSTRACT

BACKGROUND:

Total pharyngolaryngectomy (TPL) is standard treatment for hypopharyngeal cancer. However, extensive thyroidectomy and paratracheal nodal dissection (PTND) can cause hypoparathyroidism. We sought to determine the optimum extent of resection.

METHODS:

We analyzed the clinicopathological information of 161 pyriform sinus cancer patients undergoing TPL from 25 Japanese institutions. Rates of recurrence and risk factors for hypoparathyroidism, as well as incidence of pathological contralateral level VI nodal metastasis and stomal recurrence, were investigated.

RESULTS:

The extent of thyroidectomy and nodal dissection were not independent risk factors for recurrence. Incidences of contralateral level VI nodal involvement and stomal recurrence were 1.8% and 1.2%, respectively. Patients undergoing hemithyroidectomy/ipsilateral PTND did not develop stomal recurrence and had the lowest incidence of hypoparathyroidism. Prognosis in patients without tracheostomy prior to hemithyroidectomy/ipsilateral PTND was comparable to that with more extensive resections.

CONCLUSIONS:

Hemithyroidectomy/ipsilateral PTND may be sufficient for pyriform sinus cancer cases without tracheostomy.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Neoplasias Hipofaríngeas / Seio Piriforme / Hipoparatireoidismo Limite: Humans Idioma: En Revista: Head Neck Assunto da revista: NEOPLASIAS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Neoplasias Hipofaríngeas / Seio Piriforme / Hipoparatireoidismo Limite: Humans Idioma: En Revista: Head Neck Assunto da revista: NEOPLASIAS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão