Targeted delivery of herpes simplex virus glycoprotein D to CD169<sup>+</sup> macrophages using ganglioside liposomes alleviates herpes simplex keratitis in mice.

Shen, Wenhao; Wang, Chenchen; Jiang, Jiaxuan; He, Yun; Liang, Qi; Hu, Kai

Targeted delivery of herpes simplex virus glycoprotein D to CD169⁺ macrophages using ganglioside liposomes alleviates herpes simplex keratitis in mice.

Shen, Wenhao; Wang, Chenchen; Jiang, Jiaxuan; He, Yun; Liang, Qi; Hu, Kai.

Afiliação

Shen W; Department of Ophthalmology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Rd,Nanjing, Jiangsu, China. Electronic address: mf21350108@smail.nju.edu.cn.
Wang C; The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, 618 Fengqi East Rd, Hangzhou, Zhejiang, China. Electronic address: chen1113@eye.ac.cn.
Jiang J; Department of Ophthalmology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Rd,Nanjing, Jiangsu, China. Electronic address: 151230015@smail.nju.edu.cn.
He Y; Department of Ophthalmology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Rd,Nanjing, Jiangsu, China. Electronic address: heyun7@126.com.
Liang Q; Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang University School of medicine, 3 Qingchun East Road, Hangzhou, Zhejiang, China. Electronic address: 141230033@smail.nju.edu.cn.
Hu K; Department of Ophthalmology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Rd,Nanjing, Jiangsu, China. Electronic address: kai_hu@nju.edu.cn.

J Control Release ; 365: 208-218, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37981051

Assuntos

Herpes Simples; Herpesvirus Humano 1; Ceratite Herpética; Vacinas; Animais; Camundongos; Lipossomos; Linfócitos T CD8-Positivos; Gangliosídeos; Ceratite Herpética/tratamento farmacológico; Herpesvirus Humano 1/fisiologia; Córnea; Macrófagos; Glicoproteínas

Palavras-chave

CD169; Herpes simplex keratitis; Herpes simplex virus type 1 (HSV-1); Liposome; Macrophage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas / Ceratite Herpética / Herpesvirus Humano 1 / Herpes Simples Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de publicação: Holanda

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