Mesenchymal stem cell conditioned medium alleviates acute lung injury through KGF-mediated regulation of epithelial sodium channels.

Yu, Tong; Cui, Yong; Xin, Shuning; Fu, Yunmei; Ding, Yan; Hao, Liying; Nie, Hongguang

Yu, Tong; Cui, Yong; Xin, Shuning; Fu, Yunmei; Ding, Yan; Hao, Liying; Nie, Hongguang.

Afiliação

Yu T; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, Liaoning Province, China; Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, Liaoning Province, China.
Cui Y; Department of Anesthesiology, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Xin S; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, Liaoning Province, China.
Fu Y; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, Liaoning Province, China.
Ding Y; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, Liaoning Province, China.
Hao L; Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, Liaoning Province, China. Electronic address: lyhao@cmu.edu.cn.
Nie H; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, Liaoning Province, China. Electronic address: hgnie@cmu.edu.cn.

Biomed Pharmacother ; 169: 115896, 2023 Dec 31.

Article em En | MEDLINE | ID: mdl-37984305

Assuntos

Lesão Pulmonar Aguda; Células-Tronco Mesenquimais; Camundongos; Animais; Lipopolissacarídeos/toxicidade; Meios de Cultivo Condicionados/farmacologia; Meios de Cultivo Condicionados/metabolismo; Canais Epiteliais de Sódio/metabolismo; NF-kappa B/metabolismo; Fator 7 de Crescimento de Fibroblastos/farmacologia; Lesão Pulmonar Aguda/induzido quimicamente; Lesão Pulmonar Aguda/metabolismo; Células-Tronco Mesenquimais/metabolismo; Pulmão

Palavras-chave

Acute lung injury; Alveolar organoids; Epithelial sodium channels; Keratinocyte growth factor; Mesenchymal stem cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesão Pulmonar Aguda / Células-Tronco Mesenquimais Limite: Animals Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: França

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