Parenteral nutrition-related complications in older patients with acute intestinal failure: A descriptive cohort study.
JPEN J Parenter Enteral Nutr
; 48(2): 174-183, 2024 02.
Article
em En
| MEDLINE
| ID: mdl-37991279
ABSTRACT
INTRODUCTION:
Reported outcomes for parenteral nutrition (PN)-related complications in older adult patients with acute intestinal failure who are receiving PN in the acute hospital setting are limited. Our study aims to compare PN-related complications between older and younger adult patients.METHODS:
A retrospective descriptive study of inpatients who were administered PN from January 1, 2019, to December 31, 2019, was performed. Patients were categorized into older (≥65 years old) and younger (<65 years old) adult groups.RESULTS:
Two hundred thirty-five patients were included. There were 103 patients in the older adult group (mean age 73.9 [SD 6.9] years) and 132 patients in the younger adult group (mean age 52.4 [SD 12.5] years). There was a significantly higher Charlson Comorbidity Index score and lower Karnofsky score in the older adult group. The older adult group received significantly lower total energy (20.8 [SD 7.8] vs 22.8 [SD 6.3] kcal/kg/day), dextrose (3.1 [SD 1.4] vs 3.6 [SD 1.4] g/kg/day), and protein (1.1 [SD 0.4] vs 1.2 [SD 0.3] g/kg/day) than the younger group received. The mean length of stay was significantly shorter in the older adult group (35.9 [SD 21.3] vs 59.8 [SD 55.3]; P < 0.05). There was no significant difference in PN-related complications and clinical outcomes (catheter-related bloodstream infections, hypoglycemia or hyperglycemia, fluid overload, or inpatient mortality) between the two groups.CONCLUSION:
Despite more comorbidities in the older adult, the usage of PN in older adult patients with acute intestinal failure was associated with neither an increased rate of PN-related complications nor worse clinical outcomes when compared with that of younger patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Insuficiência Intestinal
/
Hiperglicemia
Limite:
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
JPEN J Parenter Enteral Nutr
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Singapura